Whitesides Research

Whitesides Group Publications: The 1980s

273."Preparation of Cytidine 5'-Monophospho-N-Acetylneuraminic Acid (CMP-NeuAc) and Uridine 5'-Diphosphoglucuronic Acid (UDP-GlcUA); Syntheses of a-2,6-Sialyllactosamine, a-2,6-Sialyllactose, and Hyaluronic Acid", Simon, E.S., Toone, E.J., Ostroff, G., Bednarski, M.D., and Whitesides, G.M., Methods Enzymol.: Complex Carbohydrates, Part F, Ginsburg, V., Eds., 1989. Download PDF

272."The Synthesis of Aldose Sugars from Half-protected Dialdehydes Using Rabbit Muscle Aldolase", Borysenko, C.W., Spaltenstein, A., Straub, J.A., and Whitesides, G.M., J. Am. Chem. Soc., 1989, 111, 9275-9276. Download PDF

271."Hemagglutinins from Two Influenza Virus Variants Bind to Sialic Acid Derivatives with Millimolar Dissociation Constants: A 500 MHz Proton Nuclear Magnetic Resonance Study", Sauter, N.K., Bednarski, M.D., Wurzburg, B.A., Hanson, J.E., Whitesides, G.M., Skehel, J.J., and Wiley, D.C., Biochemistry, 1989, 28, 8388-8396. Download PDF

270."Lactate Dehydrogenase-Catalyzed Regeneration of NAD from NADH for Use in Enzyme-Catalyzed Synthesis", Chenault, H.K., and Whitesides, G.M., Bioorg. Chem., 1989, 17, 400-409. Download PDF

269."Preparation of Phosphoenolpyruvate from D-(-)-3-Phosphoglyceric Acid for Use in Regeneration of ATP", Simon, E.S., Grabowski, S., and Whitesides, G.M., J. Am. Chem. Soc., 1989, 111, 8920-8921. Download PDF

268."Enzyme-Catalyzed Synthesis of Carbohydrates", Toone, E.J., Simon, E.S., Bednarski, M.D., and Whitesides, G.M., Tet. Rep., 1989, 45, 5365-5422. Download PDF

267."The Physical-Organic Chemistry of Surfaces, and Its Relevance to Molecular Recognition", Whitesides, G.M., and Biebuyck, H., Molecular Recognition: Chemical and Biochemical Problems, Roberts, S.M., Eds., Royal Society of Chemistry, 1989. Download PDF

266."A New, General Method for the Determination of Binding Constants: Photoacoustic Titration of Dansylamide with Carbonic Anhydrase", Jain, A., Marzluff, E.M., Jacobsen, J.R., Whitesides, G.M., and Grabowski, J.J., J. Chem. Soc. Chem. Comm., 1989, 1557-1559. Download PDF

265."Orthogonal Systems for Self-Assembled Monolayers: Alkanethiols on Gold and Alkane Carboxylic Acids on Alumina", Laibinis, P.E., Hickman, J.J., Wrighton, M.S., and Whitesides, G.M., Science, 1989, 245, 845-847. Download PDF

264."Combining Spontaneous Molecular Assembly with Microfabrication to Pattern Surfaces: Selective Binding of Isonitrile to Platinum Microwires and Characterization by Electrochemistry and Surface Spectroscopy", Hickman, J.J., Zou, C., Ofer, D., Harvey, P., Wrighton, M.S., Laibinis, P.E., Bain, C.D., and Whitesides, G.M., J. Am. Chem. Soc., 1989, 111, 7271-7272. Download PDF

263."Synthesis without Cells", Simon, E.S., Akiyama, A., and Whitesides, G.M., A Revolution in Biotechnology, Marx, J.L., Eds., ICSU Press, 1989. Download PDF

262."Modelling Organic Surfaces with Self-Assembled Monolayers", Bain, C.D., and Whitesides, G.M., Angew. Chem. Int. Ed. Engl., 1989, 28, 506-516. Download PDF

261."The Mechanism of Formation of Grignard Reagents: Trapping of Free Alkyl Radical Intermediates by Reaction with Tetramethylpiperidine-N-oxyl", Root, K.S., Hill, C.L., Lawrence, L.M., and Whitesides, G.M., J. Am. Chem. Soc., 1989, 111, 5405-5412. Download PDF

260."A Study by Contact Angle of the Acid-Base Behavior of Monolayers Containing w-Mercaptocarboxylic Acids Adsorbed on Gold: An Example of Reactive Spreading", Bain, C.D., and Whitesides, G.M., Langmuir, 1989, 5, 1370-1378. Download PDF

259."Formation of Monolayers by the Coadsorption of Thiols on Gold: Variation in the Length of the Alkyl Chain", Bain, C.D., and Whitesides, G.M., J. Am. Chem. Soc., 1989, 111, 7164-7175. Download PDF

258."Formation of Monolayers by the Coadsorption of Thiols on Gold: Variation in the Head Group, Tail Group, and Solvent", Bain, C.D., Evall, J., and Whitesides, G.M., J. Am. Chem. Soc., 1989, 111, 7155-7164. Download PDF

257."Kinetic Resolution of Unnatural and Rarely Occurring Amino Acids: Enantioselective Hydrolysis of N-Acyl Amino Acids Catalyzed by Acylase I", Chenault, H.K., Dahmer, J., and Whitesides, G.M., J. Am. Chem. Soc., 1989, 111, 6354-6364. Download PDF

256."D-Lactate Dehydrogenase: Substrate Specificity and Use as a Catalyst in the Synthesis of Homochiral 2-Hydroxy Acids", Simon, E.S., Plante, R., and Whitesides, G.M., Appl. Biochem. Biotech., 1989, 22, 169-179. Download PDF

255."Structure and Reactivity of Alkylsiloxane Monolayers Formed by Reaction of Alkyltrichlorosilanes on Silicon Substrates", Wasserman, S.R., Tao, Y.-T., and Whitesides, G.M., Langmuir, 1989, 5, 1074-1087. Download PDF

254."Monolayers of 11-Trichlorosilylundecyl Thioacetate: A System that Promotes Adhesion between Silicon Dioxide and Evaporated Gold", Wasserman, S.R., Biebuyck, H., and Whitesides, G.M., J. Mater. Res., 1989, 4, 886-891. Download PDF

253."The Structure of Self-Assembled Monolayers of Alkylsiloxanes on Silicon: A Comparison of Results from Ellipsometry and Low-Angle X-Ray Reflectivity", Wasserman, S.R., Whitesides, G.M., Tidswell, I.M., Ocko, B.M., Pershan, P.S., and Axe, J.D., J. Am. Chem. Soc., 1989, 111, 5852-5861. Download PDF

252."Comparison of Self-Assembled Monolayers on Gold: Coadsorption of Thiols and Disulfides", Bain, C.D., Biebuyck, H.A., and Whitesides, G.M., Langmuir, 1989, 5, 723-727. Download PDF

251."Attenuation Lengths of Photoelectrons in Hydrocarbon Films", Bain, C.D., and Whitesides, G.M., J. Phys. Chem., 1989, 93, 1670-1673. Download PDF

250."Characterization and Stability of Cyclic Disulfides and Cyclic Dimeric Bis(disulfides)", Houk, J., and Whitesides, G.M., Tetrahedron, 1989, 45, 91-102. Download PDF

249."Rabbit Muscle Aldolase (RAMA) as a Catalyst in Organic Synthesis", Bednarski, M.D., Simon, E.S., Bischofberger, N., Fessner, W.-D., Kim, M.-J., Lees, W., Saito, T., Waldmann, H., and Whitesides, G.M., J. Am. Chem. Soc., 1989, 111, 627-635. Download PDF

248."Enzymatic Baeyer-Villiger Type Oxidations of Ketones Catalyzed by Cyclohexanone Oxygenase", Abril, O., Ryerson, C.C., Walsh, C., and Whitesides, G.M., Bioorg. Chem., 1989, 17, 41-52. Download PDF

247."Oxidation of 2-Propanol to Acetone by Dioxygen on a Platinized Electrode under Open-Circuit Conditions", DiCosimo, R., and Whitesides, G.M., J. Phys. Chem., 1989, 93, 768-775. Download PDF

246."Liquid-Phase Oxidation of 2-Propanol to Acetone by Dioxygen Using Supported Platinum Catalysts", Nicoletti, J.W., and Whitesides, G.M., J. Phys. Chem., 1989, 93, 759-767. Download PDF

245."A Combined Chemical-Enzymatic Synthesis of 3-Deoxy-D-arabino-heptulosonic Acid 7-Phosphate", Turner, N.J., and Whitesides, G.M., J. Am. Chem. Soc., 1989, 111, 624-627. Download PDF

244."Enzymatic Methods for the Preparation of Acetyl-CoA and Analogs", Billhardt, U.-M., Stein, P., and Whitesides, G.M., Bioorg. Chem., 1989, 17, 12-Jan. Download PDF

243."Formation of Monolayer Films by the Spontaneous Assembly of Organic Thiols from Solution onto Gold", Bain, C.D., Troughton, E.B., Tao, Y.-T., Evall, J., Whitesides, G.M., and Nuzzo, R.G., J. Am. Chem. Soc., 1989, 111, 321-335. Download PDF | Supplemental

242."The Anthranilate Amide of 'Polyethylene Carboxylic Acid' Shows an Exceptionally Large Change with pH in Its Wettability by Water", Wilson, M., and Whitesides, G.M., J. Am. Chem. Soc., 1988, 110, 8718-8719. Download PDF

241."Poly(3-n-butyl-2,5-diethynylenethiophenylene): A Soluble Polymer Containing Diacetylene Units and Its Conversion to a Highly-Cross-Linked Organic Solid", Callstrom, M.R., Neenan, T.X., and Whitesides, G.M., Macromolecules, 1988, 21, 3528-3530. Download PDF

240."Hyper-Cross-Linked Organic Solids: Preparation from Poly(aryldiacetylenes) and Preliminary Measurements of their Young's Modulus, Hardness and Thermal Stability", Neenan, T.X., Callstrom, M.R., Scarmoutzos, L.M., Stewart, K.R., and Whitesides, G.M., Macromolecules, 1988, 21, 3525-3528. Download PDF

239."Formation of Two-Component Surfaces by the Spontaneous Assembly of Monolayers on Gold from Solutions Containing Mixtures of Organic Thiols", Bain, C.D., and Whitesides, G.M., J. Am. Chem. Soc., 1988, 110, 6560-6561. Download PDF

238."Materials for Advanced Electronic Devices", Whitesides, G.M., Biotechnology and Materials Science: Chemistry for the Future, Good, M.A., Eds., American Chemical Society, 1988. Download PDF

237."Depth Sensitivity of Wetting: Monolayers of w-Mercaptoethers on Gold", Bain, C.D., and Whitesides, G.M., J. Am. Chem. Soc., 1988, 110, 5897-5898. Download PDF

236."Organic Chemistry in Two Dimensions: Surface-Functionalized Polymers and Self-Assembled Monolayer Films", Whitesides, G.M., and Ferguson, G.S., Chemtracts, 1988, 1, 171-187. Download PDF

235."Cofactor Regeneration for Enzyme-Catalyzed Synthesis", Chenault, H.K., Simon, E.S., and Whitesides, G.M., Biotechnology & Genetic Engineering Reviews, Russell, G.E., Eds., Intercept, 1988. Download PDF

234."Correlation between Wettability and Structure in Monolayers in Alkanethiols Adsorbed on Gold", Bain, C.D., and Whitesides, G.M., J. Am. Chem. Soc., 1988, 110, 3665-3666. Download PDF

233."Synthesis of CMP-NeuAc from N-Acetylglucosamine: Generation of CTP from CMP using Adenylate Kinase", Simon, E.S., Bednarski, M.D., and Whitesides, G.M., Journal of the American Chemical Society, 1988, 110, 7159-7163. Download PDF

232."Synthesis of Analogs of 1,3-Dihydroxyacetone Phosphate and Glyceraldehyde-3-phosphate for Use in Studies of Fructose-1,6-Diphosphate Aldolase", Bischofberger, N., Waldmann, H., Saito, T., Simon, E.S., Lees, W., Bednarski, M.D., and Whitesides, G.M., Journal of Organic Chemistry, 1988, 53, 3457-3465. Download PDF

231."Intermolecular Activation of C-D Bonds in Benzene-d6 by trans-Neopentyl(trifluoromethanesulfonato)bis(trimethylphosphine)platinum(II)", Brainard, R.L., Nutt, W.R., Lee, T.R., and Whitesides, G.M., Organometallics, 1988, 7, 2379-2386. Download PDF

230."Enzymes as Catalysts in Organic Synthesis", Akiyama, A., Bednarski, M.., Kim, M.-J., Simon, E.S., Waldmann, H., and Whitesides, G.M., Chemtech, 1988, 627-634. Download PDF

229."Molecular-Level Control over Surface Order in Self-Assembled Monolayer Films of Thiols on Gold", Bain, C.D., and Whitesides, G.M., Science, 1988, 240, 62-63. Download PDF

228."The Synthesis of High Carbon Materials from Acetylenic Precursors. Preparation of Aromatic Monomers Bearing Multiple Ethynyl Groups", Neenan, T.X., and Whitesides, G.M., J. Org. Chem., 1988, 53, 2489-2496. Download PDF

227."L-Lactate Dehydrogenase: Substrate Specificity and Use as a Catalyst in the Synthesis of Homochiral 2-Hydroxy Acids", Kim, M.-J., and Whitesides, G.M., J. Am. Chem. Soc., 1988, 110, 2959-2964. Download PDF

226."Wetting of Functionalized Polyethylene Film Having Ionizable Organic Acids and Bases at the Polymer-Water Interface: Relations between Functional Group Polarity, Extent of Ionization, and Contact Angle with Water", Holmes-Farley, S.R., Bain, C., and Whitesides, G.M., Langmuir, 1988, 4, 921-937. Download PDF

225."Isotopic Exchange Reactions Occurring in the Hydrogenation of 1,5-Cyclooctadienedialkylplatinum(II) Complexes over Platinum Black", Miller, T.M., and Whitesides, G.M., J. Am. Chem. Soc., 1988, 110, 3164-3170. Download PDF

224."Deuterium Labeling Experiments Relevant to the Mechanism of Platinum-Catalyzed Hydrogenation of Diolefindialkylplatinum(II) Complexes: Evidence for Isotopic Exchange via Platinum Surface Hydrogen; the Stereochemistry of Reduction", Miller, T.M., McCarthy, T.J., and Whitesides, G.M., J. Am. Chem. Soc., 1988, 110, 3156-3163. Download PDF

223."Heterogeneous, Platinum-Catalyzed Hydrogenation of Diolefindialkylplatinum(II) Complexes: Kinetics", Miller, T.M., Izumi, A.N., Shih, Y.-S., and Whitesides, G.M., J. Am. Chem. Soc., 1988, 110, 3146-3156. Download PDF

222."The Structures of Self-Assembled Monolayer Films of Organosulfur Compounds Adsorbed on Gold Single Crystals: Electron Diffraction Studies", Strong, L., and Whitesides, G.M., Langmuir, 1988, 4, 546-558. Download PDF

221."Monolayer Films Prepared by the Spontaneous Self-Assembly of Symmetrical and Unsymmetrical Dialkyl Sulfides from Solution onto Gold Substrates: Structure, Properties, and Reactivity of Constituent Functional Groups", Troughton, E.B., Bain, C.D., Whitesides, G.M., Nuzzo, R.G., Allara, D.L., and Porter, M.D., Langmuir, 1988, 4, 365-385. Download PDF | Supplemental

220."The Use of Enzymes as Catalysts for Synthesis in Medicinal Chemistry: Chiral Synthons and Carbohydrates", Whitesides, G.M., and Kim, M.-J., New Methods in Drug Research, Vol. 2, Makriyannis, A., Eds., J.R. Prous, 1988. Download PDF

219."[Bis(dicyclohexylphosphino)ethane]platinum(0): Reactions with Alkyl, (Trimethylsilyl)methyl, Aryl, Benzyl, and Alkynyl Carbon-Hydrogen Bonds", Hackett, M., and Whitesides, G.M., J. Am. Chem. Soc., 1988, 110, 1449-1462. Download PDF

218."The Activation of the C-H Bonds of Benzene by Reaction with [Bis(dicyclo-hexylphosphino)ethane]platinum(0), Generated by the Thermolysis of cis-[Bis(dicyclohexylphosphino)ethane](hydride)(neopentyl)platinum(II)", Hackett, M., Ibers, J.A., and Whitesides, G.M., J. Am. Chem. Soc., 1988, 110, 1436-1448. Download PDF

217."Generation of Cytidine 5'-Triphosphate Using Adenylate Kinase", Simon, E.S., Bednarski, M.D., and Whitesides, G.M., Tet. Lett., 1988, 29, 1123-1126. Download PDF

216."Synthesis of 3-Deoxy-D-manno-2-octulosonate-8-phosphate (KDO-8-P) from D-Arabinose: Generation of D-Arabinose-5-Phosphate Using Hexokinase", Bednarski, M.D., Crans, D.C., DiCosimo, R.., Simon, E.S., Stein, P.D., and Whitesides, G.M., Tet. Lett., 1988, 29, 427-430. Download PDF

215."Carlons: Organic Polymers from Condensation of Carbon Dinucleophiles with Difunctional Derivatives of Carboxylic Acids", Kool, L.B., and Whitesides, G.M., J. Am. Chem. Soc., 1988, 110, 306-307. Download PDF

214."Enzyme-Catalyzed Synthesis of Nucleoside Triphosphates from Nucleoside Monophosphates: ATP from AMP and Ribavirin 5'-triphosphate from Ribavirin 5'-monophosphate", Kim, M.-J., and Whitesides, G.M., Appl. Biochem. Biotech., 1987, 16, 95-108. Download PDF

213."Enzymatic Regeneration of Adenosine 5'-Triphosphate: Acetyl Phosphate, Phosphoenylpyruvate, Methoxycarbonyl Phosphate, Dihydroxyacetone Phosphate, 5-Phospho-a-D-ribosyl Pyrophosphate, Uridine-5'-diphosphoglucose", Crans, D.C., Kazlauskas, R.J., Hirschbein, B.L., Wong, C.-H., Abril, O., and Whitesides, G.M., Methods Enzymol.: Immobilized Enzymes/Cells, Pt. C, Mosbach, K., Eds., 1987. Download PDF

212."Protein Synthesis in Cell-Free Reticulocyte Lysates on Multi-Hour Incubation", Findeis, M.A., and Whitesides, G.M., Appl. Biochem. Biotech., 1987, 15, 169-189. Download PDF

211."A Combined Microbial/Chemical Synthesis of (+)-(R)-Methlyoxirane Having High Enantiomeric Excess", Simon, E., Whitesides, G.M., Cameron, D.C., Weitz, D.A., and Cooney, C.L, Journal of Organic Chemistry , 1987, 52, 4042-4044. Download PDF

210."The Measurement of Thiol-Disulfide Interchange Reactions and Thiol pKa Values", Houk, J., Singh, R., and Whitesides, G.M., Methods in Enzymology: Sulfur and Sulfur Amino Acids, Jakoby, W.B.., and Griffith, O.W., Eds., Academic Press, 1987, 143. Download PDF

209."Structure-Reactivity Relations for Thiol-Disulfide Interchange", Houk, J., and Whitesides, G.M., J. Am. Chem. Soc., 1987, 109, 6825-6836. Download PDF

208."What, If Anything, Can Chemistry Offer to Fracture Mechanics?", Whitesides, G.M., and Neenan, T.X., Chemistry and Physics of Fracture, NATO ASI Series E: Applied Sciences - No. 130, Latanision, R.M., Eds., 1987. Download PDF

207."Enzymes in Organic Synthesis", Waldmann, H., and Whitesides, G.M., Ullmann's Encyclopedia of Industrial Chemistry, A9: "Enzymes", Apre, H-J., Eds., Wiley-VCH, 1987. Download PDF

206."Limited Nerve Impulse Blockade by 'Leashed' Local Anesthetics", Butterworth, J.F., Moran, J.R., Whitesides, G.M., and Strichartz, G.R., J. Med. Chem., 1987, 30, 1295-1302. Download PDF

205."A Short Synthesis of Ambrox™ from Sclareol", Decorzant, R., Vial, C., Naf, F., and Whitesides, G.M., Tetrahedron, 1987, 43, 1871-1879. Download PDF

204."Enzymes as Catalysts in Practical Organic Synthesis", Akiyama, A., Bednarski, M., M.-J., E.S..S.K., Waldmann, H., and Whitesides, G.M., Chem. Britain, 1987, 23, 645-654. Download PDF

203."The Enantiomeric Purity of Polar Substrates Can Be Determined with Chiral Lanthanide NMR Shift Reagents in Polar Solvents", Sweeting, L.M., Crans, D.C., and Whitesides, G.M., J. Org. Chem., 1987, 52, 2273-2276. Download PDF

202."Fumarase-Catalyzed Synthesis of L-threo-Chloromalic Acid, and Its Conversion to 2-Deoxy-D-Ribose and D-erythro-Sphingosine", Findeis, M.A., and Whitesides, G.M., J. Org. Chem., 1987, 52, 2838-2848. Download PDF

201."Regeneration of Nicotinamide Cofactors for Use in Enzymatic Synthesis", Chenault, K., and Whitesides, G.M., Appl. Biochem. Biotech., 1987, 14, 147-197. Download PDF

200."Enzymatic Routes to Enantiomerically Enriched 1-Butene Oxide", Chenault, H.K., Kim, M.-J., Akiyama, A., Miyazawa, T., Simon, E., and Whitesides, G.M., J. Org. Chem., 1987, 52, 2608-2611. Download PDF

199."Membrane-Enclosed Enzymatic Catalysis (MEEC): A Useful, Practical Method for the Manipulation of Enzymes in Organic Synthesis", Bednarski, M.D., Chenault, H.K., Simon, E.S., and Whitesides, G.M., J. Am. Chem. Soc., 1987, 109, 1283-1285. Download PDF

198."Reconstruction of the Interface of Oxidatively Functionalized Polyethylene (PE-CO2H) and Derivatives on Heating", Holmes-Farley, S.R., Reamey, R.H., Nuzzo, R., McCarthy, T.J., and Whitesides, G.M., Langmuir, 1987, 3, 799-815. Download PDF

197."The Synthesis and Thermolysis of Dimethylbis(trialkylphosphine)-platinum(II) Complexes in Which the Phosphine Ligands Contain Adamantyl, Adamantylmethyl, and Methyl Groups", Hackett, M., and Whitesides, G.M., Organometallics, 1987, 6, 403-410. Download PDF

196."The Enzymatic Utilization of Sucrose in the Synthesis of Amylose and Derivatives of Amylose Using Phosphorylases", Waldmann, H., Gygax, D., Bednarski, M., Shangraw, W.R., and Whitesides, G.M., Carbohyd. Res., 1986, 157, c4-c7. Download PDF

195."The Reactivity of Carboxylic Acid and Ester Groups in the Functionalized Interfacial Region of 'Polyethylene Carboxylic Acid' (PE-CO2H) and Derivatives: Differentiation of the Functional Groups into Shallow and Deep Subsets Based on a Comparison of Contact Angle and ATR-IR Measurements", Holmes-Farley, S.R., and Whitesides, G.M., Langmuir, 1986, 3, 62-76. Download PDF

194."Cis[bis(dicyclohexylphosphino)ethane]platinum(0) Reacts with Unactivated Carbon-Hydrogen Bonds", Hackett, M., Ibers, J.A., Jernakoff, P., and Whitesides, G.M., J. Am. Chem. Soc., 1986, 108, 8094-8095. Download PDF

193."Aldolase-Catalyzed Synthesis of Complex C8 and C9 Monosaccharides", Bednarski, M.D., Waldmann, H.J., and Whitesides, G.M., Tet. Lett., 1986, 5807-5810. Download PDF

192."Synthesis of a Water-Soluble Derivative of Cyclohexatriacontane-1,2,13,14,25,26-hexone", Mandeville, W.H., and Whitesides, G.M., J. Org. Chem., 1986, 51, 3257-3261. Download PDF

191."Radical Isomerization during Grignard Reagent Formation. A Quantitative Treatment", Garst, J.F., Deutch, J.E., and Whitesides, G.M., J. Am. Chem. Soc., 1986, 108, 2490-2491. Download PDF

190."The Role of Chemistry in Materials Science", Whitesides, G.M., Wrighton, M.S., and Parshall, G., Advancing Materials Research, National Academy of Sciences, 1986. Download PDF

189."Improved Adhesion of Thin Conformal Organic Films to Metal Surfaces", Stewart, K.R., Whitesides, G.M., Godfried, H.P., and Silvera, I.F., Rev. Sci. Instrum., 1986, 57, 1381-1383. Download PDF

188."The Mechanisms of Thermal Decomposition of trans-Chloroneopentylbis(tricyclopentylphosphine)platinum(II)", Brainard, R.L., Miller, T.M., and Whitesides, G.M., Organometallics, 1986, 5, 1481-1490. Download PDF

187."Fluorescence Properties of Dansyl Groups Covalently Bonded to the Surface of Oxidatively Functionalized Low-Density Polyethylene Film", Holmes-Farley, S.R., and Whitesides, G.M., Langmuir, 1986, 2, 266-282. Download PDF

186."The Mechanism of Thermal Decomposition of Bis(tricyclopentylphosphine)-platinacyclopentane(II): Intramolecular b-Hydride Elimination from the Platinacyclopentane Ring is Slow Relative to an Intermolecular Chain Reaction Involving Hydridoplatinum Intermediates", Miller, T.M., and Whitesides, G.M., Organometallics, 1986, 5, 1473-1480. Download PDF

185."Preparation of Optically Active 1,2-Diols and a-Hydroxyketones Using Glycerol Dehydrogenase as Catalyst: Limits to Enzyme-Catalyzed Synthesis Due to Non-competitive and Mixed Inhibition by Product", Lee, L.G., and Whitesides, G.M., J. Org. Chem., 1986, 51, 25-36. Download PDF

184."Acid-Based Behavior of Carboxylic Acid Groups Covalently Attached at the Surface of Polyethylene: The Usefulness of Contact Angle in Following the Ionization of Surface Functionality", Holmes-Farley, S.R., Reamey, R.H., McCarthy, T.J., Deutch, J., and Whitesides, G.M., Langmuir, 1985, 1, 725-740. Download PDF

183."Glycerol Kinase: Synthesis of Dihydroxyacetone Phosphate, sn-Glycerol-3-Phosphate, and Chiral Analogues", Crans, D.C., and Whitesides, G.M., J. Am. Chem. Soc., 1985, 107, 7019-7027. Download PDF

182."Glycerol Kinase: Substrate Specificity", Crans, D.C., and Whitesides, G.M., J. Am. Chem. Soc., 1985, 107, 7008-7018. Download PDF

181."Enzymes as Catalysts in Synthetic Organic Chemistry", Whitesides, G.M., and Wong, C.-H., Angew. Chem. Int. Ed. Engl., 1985, 24, 617-638. Download PDF

180."Enzyme-Catalyzed Organic Synthesis: A Comparison of Strategies for in situ Regeneration of NAD from NADH", Lee, L.G., and Whitesides, G.M., J. Am. Chem. Soc., 1985, 107, 6999-7008. Download PDF

179."Suppression of Unwanted Heterogeneous Platinum(0)-Catalyzed Reactions by Poisoning with Mercury(0) in Systems Involving Competing Homogeneous Reactions of Soluble Organoplatinum Compounds: Thermal Decomposition of Bis(triethylphosphine)-3,3,4,4-tetramethylplatinacyclopentane", Whitesides, G.M., Hackett, M., Brainard, R.L., Lavalleye, J.-P.P.M., Sowinski, A.F., Izumi, A.N., Moore, S.S., Brown, D.W., and Staudt, E.M., Organometallics, 1985, 4, 1819-1830. Download PDF

178."The Mechanism of Thermal Decomposition of trans-Chloroethylbis-(triethylphosphine)platinum(II)", Brainard, R.L., and Whitesides, G.M., Organometallics, 1985, 4, 1550-1557. Download PDF

177."Enzymatic Synthesis of DeoxyATP Using DNA as Starting Material", Ladner, W.E., and Whitesides, G.M., J. Org. Chem., 1985, 50, 1076-1079. Download PDF

176."Organic Synthesis Using Enzymes", Whitesides, G.M., Organic Chemical Synthesis Using Enzymes, Ciba Foundation Symposium No. 111, Ciba Foundation, 1985. Download PDF

175."Synthesis of Methoxycarbonyl Phosphate, A New Reagent Having High Phosphoryl Donor Potential for Use in ATP Cofactor Regeneration", Kazlauskas, R.J., and Whitesides, G.M., J. Org. Chem., 1985, 50, 1069-1076. Download PDF

174."Organic Chemicals from Marine Sources", Whitesides, G.M., and Elliot, J., Biotechnology in the Marine Sciences, Colwell, R.M., Pariser, E.R., and Sinskey, A.J., Eds., John Wiley, 1984. Download PDF

173."Lipase-Catalyzed Hydrolysis as a Route to Esters of Chiral Epoxy Alcohols", Ladner, W.E., and Whitesides, G.M., J. Am. Chem. Soc., 1984, 106, 7250-7251. Download PDF

172."Enzymatic Methods in Organic Synthesis", Findeis, M.A., and Whitesides, G.M., Ann. Rep. Med. Chem., 1984, 19, 263-272. Download PDF

171."Enzymatic Synthesis of Arginine Phosphate with Coupled ATP Cofactor Regeneration", Bolte, J., and Whitesides, G.M., Bioorg. Chem., 1984, 12, 170-175. Download PDF

170."A Practical Enzymatic Synthesis of (SP)-Adenosine 5'-O-(1-Thiotriphosphate)((SP)-ATP-a-S)", Moran, J.R., and Whitesides, G.M., J. Org. Chem., 1984, 49, 704-706. Download PDF

169."Practical Enzymatic Synthesis of Adenosine-5'-O-(3-Thiophosphate)(ATP-g-S)", Abril, O., Crans, D.C., and Whitesides, G.M., J. Org. Chem., 1984, 49, 1360-1364. Download PDF

168."An Efficient Chemical and Enzymatic Synthesis of Nicotinamide Adenine Dinucleotide (NAD+)", Walt, D.R., Rios-Mercadillo, V.M., Augé, J., and Whitesides, G.M., J. Am. Chem. Soc., 1984, 106, 234-239. Download PDF

167."The Mechanism of Hydrogenolysis of Dineopentylbis(triethylphosphine)platinum(II)", Reamey, R.H., and Whitesides, G.M., J. Am. Chem. Soc., 1984, 106, 81-85. Download PDF

166."Organometallic Reactions of Platinum Involving Metallic Hydrides", Whitesides, G.M., Reamey, R.H., Brainard, R.L., Izumi, A.N., and McCarthy, T.J., Annals New York Acad. Sci., 1983, 415, 56-66. Download PDF

165."Chemical Modification of Acrylamide Gels: Verification of the Role of Ionization in Phase Transitions", Nicoli, D., Young, C., Tanaka, T., Pollak, A., and Whitesides, G.M., Macromolecules, 1983, 16, 887-890. Download PDF

164."Magnetic Separations in Biotechnology", Whitesides, G.M., Kazlauskas, R., and Josephson, L., TIBTECH, 1983, 1, 144-148. Download PDF

163."Practical Synthesis of 5-Phospho-D-ribosyl-a-1-pyrophosphate (PRPP): Enzymatic Routes from Ribose-5-phosphate or Ribose", Gross, A., Abril, O., Lewis, J.M., Geresh, S., and Whitesides, G.M., J. Am. Chem. Soc., 1983, 105, 7428-7434. Download PDF

162."Enzymes as Catalysts in Organic Synthesis", Whitesides, G.M., and Wong, C.-H., Aldrichimica Acta, 1983, 16, 27-34. Download PDF

161."A Convenient Synthesis of Disodium Acetyl Phosphate for Use in situ ATP Cofactor Regeneration", Crans, D.C., and Whitesides, G.M., J. Org. Chem., 1983, 26, 3130-3132. Download PDF

160."Enzymatic Synthesis of S-Adenosyl-L-Methionine from L-Methionine and ATP", Gross, A., Geresh, S., and Whitesides, G.M., Appl. Biochem. Biotech., 1983, 8, 415-422. Download PDF

159."Enzyme-Catalyzed Organic Synthesis: Regeneration of Deuterated Nicotinamide Cofactors for Use in Large-Scale Enzymatic Synthesis of Deuterated Substances", Wong, C.-H., and Whitesides, G.M., J. Am. Chem. Soc., 1983, 105, 5012-5014. Download PDF

158."Synthesis of Sugars by Aldolase-Catalyzed Condensation Reactions", Wong, C.-H., and Whitesides, G.M., J. Org. Chem., 1983, 48, 3199-3205. Download PDF

157."Chemical and Enzymatic Synthesis of 6-Deoxyhexoses. Conversion to 2,5-Dimethyl-4-Hydroxy-2,3-Dihydro-furan-3-one (Furaneol©) and Analogues", Wong, C.-H., and Whitesides, G.M., J. Org. Chem., 1983, 48, 3493-3497. Download PDF

156."Activation Parameters for Thiolate-Disulfide Interchange", Whitesides, G.M., Houk, J., and Patterson, M.A.K., J. Org. Chem., 1983, 48, 112-115. Download PDF

155."Relations between Fracture and Coordination Chemistry", Whitesides, G.M., Atomistics of Fracture, Latanision, R.M., and Pickens, J.R., Eds., Plenum Press, 1983. Download PDF

154."Preparation of a Mixture of Nucleoside Triphosphates from Yeast RNA: Use in Enzymatic Synthesis Requiring Nucleoside Triphosphate Regeneration, and Conversion to Nucleoside Diphosphate Sugars", Wong, C.-H., Haynie, S.L., and Whitesides, G.M., J. Am. Chem. Soc., 1983, 105, 115-117. Download PDF

153."Enzyme-Catalyzed Synthesis of N-Acetyllactosamine with in situ Regeneration of Uridine 5'-Diphosphate Glucose and Uridine 5'-Diphosphate Galactose", Wong, C.-H., Haynie, S.L., and Whitesides, G.M., J. Org. Chem., 1982, 47, 5416-5418. Download PDF

152."Ribulose-1,5-Biphosphate: Routes from Glucose-6-Phosphate (via 6-Phosphogluconate and Ribulose-5-phosphate) and from Adenosine Monophosphate (via Ribose-5-phosphate and Ribulose-5-phosphate)", Wong, C.-H., Pollak, A., McCurry, S.D., Sue, M.M., Knowles, J.R., and Whitesides, G.M., Methods in Enzymology, Wood, W.A., Eds., Academic Press, 1982, 89. Download PDF

151."Asymmetric Synthesis Using Cofactor-Requiring Enzymes", Whitesides, G.M., Wong, C.-H., and Pollak, A., Asymmetric Reactions and Processes in Chemistry, Eliel, E., and Otsuka, S., Eds., American Chemical Society, 1982, 185. Download PDF

150."Synthesis of Phosphoenolpyruvate and Its Use in ATP Cofactor Regeneration", Hirschbein, B.L., Mazenod, F.P., and Whitesides, G.M., J. Org. Chem., 1982, 47, 3765-3766. Download PDF

149."Enzyme-Catalyzed Transhydrogenation between Nicotinamide Cofactors and Its Application in Organic Synthesis", Wong, C.-H., and Whitesides, G.M., J. Am. Chem. Soc., 1982, 104, 3542-3544. Download PDF

148."Enzyme-Catalyzed Organic Synthesis: NAD(P)H Cofactor Regeneration Using Ethanol/Alcohol Dehydrogenase/Aldehyde Dehydrogenase and Methanol/Alcohol Dehydrogenase/Aldehyde Dehydrogenase/Formate Dehydrogenase", Wong, C.-H, and Whitesides, G.M., J. Org. Chem., 1982, 47, 2816-2818. Download PDF

147."Laboratory-Scale Enzymatic/Chemical Synthesis of D- and L-b-Chlorolactic Acid and D- and L-Potassium Glycidate", Hirschbein, B.L., and Whitesides, G.M., J. Am. Chem. Soc., 1982, 104, 4458-4460. Download PDF

146."Reductive Elimination of a Carbon-Carbon Bond from Bis(trialkylphosphine)-3,3-dimethylplatinacyclopropane Produces Bis(trialkylphosphine)-platinum(0) and 1,1-Dimethylcyclopropane", DiCosimo, R., and Whitesides, G.M., J. Am. Chem. Soc., 1982, 104, 3601-3607. Download PDF

145."Synthesis and Coordinating Properties of Heterocyclic Tertiary Phosphines", Moore, S.S., and Whitesides, G.M., J. Org. Chem., 1982, 47, 1489-1493. Download PDF

144."Magnetic Separations in Chemistry and Biochemistry", Hirschbein, B.L., Brown, D.W., and Whitesides, G.M., Chemtech., 1982, 12, 172-179. Download PDF

143."Reductive Elimination of H-H, H-CH3, and CH3-CH3 from Bis(phosphine)-platinum(II), -palladium(II), and -nickel(II) Complexes: A Theoretical Study Using the SCF-Xa-SW Method", Balazs, A.C., Johnson, K.H., and Whitesides, G.M., Inorg. Chem., 1982, 21, 2162-2174. Download PDF

142."Structures of Dineopentylbis(triethylphosphine)platinum(II) and Bis(triethylphosphine)-3,3-dimethylplatinacyclobutane: Reactant and Product in a Thermal Cyclometallation Reaction", Ibers, J.C., DiCosimo, R., and Whitesides, G.M., Organometallics, 1982, 1, 13-20. Download PDF

141."Affinity Separation of Enzymes from Mixtures Containing Suspended Solids: Comparisons of Magnetic and Non-Magnetic Techniques", Hirschbein, B.L., and Whitesides, G.M., Appl. Biochem. Biotech., 1982, 7, 157-176. Download PDF

140."Hybrid Organometallic/Enzymatic Catalyst Systems: Regeneration of NADH Using Dihydrogen", Abril, O., and Whitesides, G.M., J. Am. Chem. Soc., 1982, 104, 1552-1554. Download PDF

139."Cyclometalation of Dialkylbis(triethylphosphine)platinum(II) Complexes: Formation of Pt, Pt-Bis(triethylphosphine)platinacycloalkanes", DiCosimo, R., Moore, S.S., Sowinski, A.F., and Whitesides, G.M., J. Am. Chem. Soc., 1982, 104, 124-133. Download PDF

138."Enzymatic Conversion of a-Ketoaldehydes to Optically Active a-Hydroxacids Using Glyoxalase I and II", Patterson, M.A.K., Szajewski, R.P., and Whitesides, G.M., J. Org. Chem., 1981, 46, 4682-4685. Download PDF

137."Regeneration of NAD(P)H Using Glucose-6-Sulfate and Glucose-6-Phosphate Dehydrogenase", Wong, C.-H., Gordon, J., Cooney, C.L., and Whitesides, G.M., J. Org. Chem., 1981, 46, 4676-4679. Download PDF

136."Enzyme-Catalyzed Organic Synthesis: Electrochemical Regeneration of NAD(P)H from NAD(P) Using Methyl Viologen and Flavoenzymes", DiCosimo, R., Wong, C.-H., Daniels, L., and Whitesides, G.M., J. Org. Chem., 1981, 46, 4622-4623. Download PDF

135."A Combined Electrochemical/Enzymatic Method for in situ Regeneration of NADH Based on Cathodic Reduction of Cyclic Disulfides", Shaked, Z., Barber, J.J., and Whitesides, G.M., J. Org. Chem., 1981, 46, 4100-4101. Download PDF

134."Enzyme-Catalyzed Organic Synthesis: NAD(P)H Regeneration Using Dihydrogen and the Hydrogenase from Methanobacter thermoautotrophicum", Wong, C.-H., Daniels, L., Orme-Johnson, W.H., and Whitesides, G.M., J. Am. Chem. Soc., 1981, 103, 6227-6228. Download PDF

133."Synthesis of Functional Chelating Diphosphines Containing the Bis[2-(diphenylphosphino)ethyl]amino Moiety and the Use of These Materials in the Preparation of Water-Soluble Diphosphine Complexes of Transition Metals", Nuzzo, R.G., Haynie, S.L., Wilson, M.E., and Whitesides, G.M., J. Org. Chem., 1981, 46, 2861-2867. Download PDF

132."The Mechanism of Formation of Grignard Reagents. The Rate of Reaction of Cyclopentyl Bromide with a Rotating Magnesium Disk", Root, K.S., Deutch, J., and Whitesides, G.M., J. Am. Chem. Soc., 1981, 103, 5475-5479. Download PDF

131."Heterogenous Platinum-Catalyzed Hydrogenation of Dialkyl(diolefin)platinum(II) Complexes", McCarthy, T.J., Shih, Y.-S., and Whitesides, G.M., Proc. Nat. Acad. Sci. USA, 1981, 78, 4649-4651. Download PDF

130."The Mechanisms of Thermal Decomposition of Dialkylbis(triethylphosphine)platinum(II) Complexes", Whitesides, G.M., Pure Appl. Chem., 1981, 53, 287-292. Download PDF

129."Enzyme-Catalyzed Organic Synthesis: NAD(P)H Cofactor Regeneration Using Glucose-6-Phosphate and the Glucose-6-Phosphate Dehydrogenase from Leuconostoc mesenteroides", Wong, C.-H., and Whitesides, G.M., J. Am. Chem. Soc., 1981, 103, 4890-4899. Download PDF

128."Apparent Fluxionality in Diethyl(phosphine)platinum(II), a Coordinately Unsaturated Intermediate in b-Hydride Elimination", McCarthy, T.J., Nuzzo, R.G., and Whitesides, G.M., J. Am. Chem. Soc., 1981, 103, 1676-1678. Download PDF

127."Thermal Decomposition of Di(Cycloalkyl)bis(triethylphosphine)platinum-(II) Complexes", Nuzzo, R.G., McCarthy, T.J., and Whitesides, G.M., J. Am. Chem. Soc., 1981, 103, 3404-3410. Download PDF

126."Mechanisms of Thermal Decomposition of Diethylbis(triethylphosphine)-platinum(II)", McCarthy, T.J., Nuzzo, R.G., and Whitesides, G.M., J. Am. Chem. Soc., 1981, 103, 3396-3403. Download PDF

125."Ring Strain in Bis(triethylphosphine)-3,3-dimethylplatinacyclobutane is Small", Moore, S.S., DiCosimo, R., Sowinski, A.F., and Whitesides, G.M., J. Am. Chem. Soc., 1981, 103, 948-949. Download PDF

124."Preparation of Tertiary Phosphine-Olefin Complexes of Platinum(0): A Convenient Synthesis of Ethylenebis(triethylphosphine)platinum(0)", Nuzzo, R.G., McCarthy, T.J., and Whitesides, G.M., Inorg. Chem., 1981, 20, 1312-1314. Download PDF

123."Practical Enzymatic Syntheses of Ribulose-1,5-diphosphate and Ribose-5-phosphate", Wong, C-H., McCurry, S.D., and Whitesides, G.M., J. Am. Chem. Soc., 1980, 102, 7938-7939. Download PDF

122."Synthesis of Nicotinamide Adenine Dinucleotide (NAD) from Adenosine Monophosphate (AMP)", Walt, D.R., Rios-Mercadillo, V.M., Augé, J., and Whitesides, G.M., J. Am. Chem. Soc., 1980, 102, 7805-7806. Download PDF

121."Enzyme-Catalyzed Organic Synthesis: NADH Regeneration Using Formate Dehydrogenase", Shaked, Z., and Whitesides, G.M., J. Am. Chem. Soc., 1980, 102, 7104-7105.

120."Enzyme Immobilization by Condensation Copolymerization into Cross-linked Polyacrylamide Gels", Pollak, A., Blumenfield, H., Wax, M., Baughn, R.L., and Whitesides, G.M., J. Am. Chem. Soc., 1980, 102, 6324-6336. Download PDF

119."Organic Synthesis Using Cofactor-Requiring Enzymes", Whitesides, G.M., Enzymes: The Interface between Technology and Economics, Danehy, J.P., and Wolnak, B., Eds., Marcel Dekker, Inc., 1980. Download PDF

118."The Mechanism of Thermal Decomposition of Dineopentylbis(triethyl-phosphine)platinum(II): Formation of Bis(triethylphosphine)-3,3-dimethylplatinacyclobutane", Foley, P., DiCosimo, R., and Whitesides, G.M., J. Am. Chem. Soc., 1980, 102, 6713-6725. Download PDF

117."Rates of Thiol-Disulfide Interchange Reactions Involving Proteins, and Kinetic Measurements of Thiol pKa Values", Shaked, Z., Szajewski, R.P., and Whitesides, G.M., Biochemistry, 1980, 19, 4156-4166. Download PDF

116."Trappings of Free Alkyl Radical Intermediates in the Reaction of Alkyl Bromides with Magnesium", Lawrence, L.M., and Whitesides, G.M., J. Am. Chem. Soc., 1980, 102, 2493-2494. Download PDF

115."Reactions of Tetrakis(triphenylphosphine)platinum(0) and Ethylenebis(triphenylphosphine)platinum(0) with Strong Proton Acids", Foley, P., and Whitesides, G.M., Inorg. Chem., 1980, 19, 1402-1404. Download PDF

114."The Mechanism of Formation of Grignard Reagents: Corrosion of Metallic Magnesium by Alkyl Halides in Ethers", Hill, C.L., Sande, J.B.V., and Whitesides, G.M., J. Org. Chem., 1980, 45, 1020-1028. Download PDF

113."Rate Constants and Equilibrium Constants for Thiol-Disulfide Interchange Reactions Involving Oxidized Gluthathione", Szajewski, R.P., and Whitesides, G.M., J. Am. Chem. Soc., 1980, 102, 2011-2026. Download PDF

112."Reductive Cleavage of Carbon-Halogen Bonds by Tri-n-butyltin Hydride, Lithium 4,4'-Dimethylbenzophenone Ketyl, and Metallic Magnesium", Barber, J.J., and Whitesides, G.M., J. Am. Chem. Soc., 1980, 102, 239-243. Download PDF

111."The Mechanism of Formation of Grignard Reagents: The Kinetics of Reaction of Substituted Aryl Bromides with Magnesium and with Tri-n-butyltin Hydride in Ethereal Solvents", Roberts, H.R., Rogers, H.R., Mitchell, H.L., and Whitesides, G.M., J. Am. Chem. Soc., 1980, 102, 231-238. Download PDF

110."The Mechanism of Formation of Grignard Reagents: The Rate of Reaction of Cyclopentyl Bromide with Magnesium is Transport-Limited in Diethyl Ether", Rogers, H.R., Deutch, J., and Whitesides, G.M., J. Am. Chem. Soc., 1980, 102, 226-231. Download PDF

109."The Mechanism of Formation of Grignard Reagents: The Kinetics of Reaction of Alkyl Halides in Diethyl Ether with Magnesium", Rogers, H.R., Hill, C.L., Fijiwara, Y., Rogers, R.J., Mitchell, H.L., and Whitesides, G.M., J. Am. Chem. Soc., 1980, 102, 217-226. Download PDF

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