E. T. Mack, P. W. Snyder, R. Perez-Castillejos, and G. M. Whitesides. 2011. “Using Covalent Dimers of Human Carbonic Anhydrase II to Model Bivalency in Immunoglubulins.” J. Amer. Chem. Soc., 133, Pp. 11701-11715.Abstract PDF Supplemental

B. F. Shaw, H. Arthanari, A. Lee, A. Durazo, D.P Frueh, M. P. Pollastri, B. Bilgicer, S. P. Gygi, G. Wagner, and G. M. Whitesides. 2010. “Neutralizing Positive Charges at the Surface of a Protein Lowers its Rate of Amide Hydrogen Exchange without Altering its Structure or Increasing its Thermostability.” J. Amer. Chem. Soc., 132, Pp. 17411-17425.Abstract PDF Supplemental

C. Cheng, A. W. Martinez, J. Gong, C. R. Mace, S. T. Phillips, E. Carrilho, K. A. Mirica, and G. M. Whitesides. 2010. “Paper-Based ELISA.” Angew. Chemie., 122, Pp. 4881-4884. PDF Supplemental

V.M. Krishnamurthy, G. K. Kaufman, A. R. Urbach, I. Gitlin, K. L. Gudiksen, D. B. Weibel, and G. M. Whitesides. 2008. “Carbonic Anhydrase as a Model for Biophysical and Physical-Organic Studies of Proteins and Protein-Ligand Binding.” Chemical Reviews, 108, Pp. 946-1051. 1010.pdf

G. M. Whitesides, P. W. Snyder, D. T. Moustakas, and K. A. Mirica. 2008. “Designing Ligands to Bind Tightly to Proteins.” In Physical Biology: From Atoms to Medicine, edited by A. H. Zewail, 9th ed., Pp. 189-215. London: Imperial College Press. PDF

E. T. Mack, R. Perez-Castillejos, Z. Suo, and G. M. Whitesides. 2008. “Exact Analysis of Ligand-Induced Dimerization of Momomeric Receptors.” Analytical Chemistry, 80, Pp. 5550-5555. PDF

B. F. Shaw, G. F. Schneider, B. Bilgicer, G. K. Kaufman, J. M. Neveu, W. S. Lane, J. P. Whitelegge, and G. M. Whitesides. 2008. “Lysine Acetylation can Generate Highly Charged Enzymes with Increased Resistance Towards Irreversible Inactivation.” Protein Science, 17, Pp. 1446-1455. PDF

M. Mayer, V. Semetey, I. Gitlin, J. Yang, and G. M. Whitesides. 2008. “Using Ion Channel-Forming Peptides to Quantify Protein-Ligand Interactions.” J. Amer. Chem. Soc., 130, Pp. 1453-1465. 1007.pdf

V.M. Krishnamurthy, V. Semetey, P. J. Bracher, N. Shen, and G. M. Whitesides. 2007. “Dependence of Effective Molarity on Linker Length for an Intramolecular Protein-Ligand System.” J. Amer. Chem. Soc., 129, Pp. 1312-1320. 979.pdf

J. Su, R. R. Brau, X. Jiang, G. M. Whitesides, M. J. Lang, and P. T. C. So. 2007. “Geometric Confinement Influences Cellular Mechanical Properties II - Intracellular Variances in Polarized Cells.” Mol. Cell. Biomech., 4, Pp. 105-118. 992.pdf

J. Su, X. Jiang, R. Welsch, G. M. Whitesides, and P. T. C. So. 2007. “Geometric Confinement Influences Cellular Mechanical Properties I - Adhesion Area Dependence.” Mol. Cell. Biomech., 4, Pp. 87-104. 991.pdf

B. Bilgicer, D. T. Moustakas, and G. M. Whitesides. 2007. “A Synthetic Trivalent Hapten that Aggregates Anti-2, 4-DNP IgGs into Bicyclic Trimers.” J. Amer. Chem. Soc., 129, Pp. 3722-3728. 987.pdf

V.M. Krishnamurthy, B. R. Bohall, D. T. Moustakas, and G. M. Whitesides. 2007. “Thermodynamic Parameters for the Association of Fluorinated Benzenesulfonamides with Bovine Carbonic Anhydrase II.” Chemistry: An Asian Journal, 2, Pp. 94-105. 1005.pdf

K. L. Gudiksen, I. Gitlin, and G. M. Whitesides. 2006. “Differentiation of Proteins based on Characteristic Patterns of Association and Denaturation in Solutions of Sodium Dodecyl Sulfate.” Proc. Natl. Acad. Sci. USA, 103, Pp. 7968-7972. PDF

I. Gitlin, K. L. Gudiksen, and G. M. Whitesides. 2006. “Effects of Surface Charge on Denaturation of Bovine Carbonic Anhydrase.” ChemBioChem, 7, Pp. 1241-1250. 962.pdf

K. L. Gudiksen, I. Gitlin, D. T. Moustakas, and G. M. Whitesides. 2006. “Increasing the Net Charge and Decreasing the Hydrophobicity of Bovine Carbonic Anhydrase Decreases the Rate of Denaturation with Sodium Dodecyl Sulfate.” Biophysical Journal, 91, Pp. 298-310. PDF

V.M. Krishnamurthy, L. A. Estroff, and G. M. Whitesides. 2006. “Multivalency in Ligand Design.” In Fragment-based Approaches in Drug Discovery, edited by R. Mannhold, H. Kubinyi, and G. Folkers, 34: Pp. 11-53. Weinheim: WILEY-VCH Verlag GmbH & Co. 963.pdf

V.M. Krishnamurthy, B. R. Bohall, V. Semetey, and G. M. Whitesides. 2006. “The Paradoxical Themodynamic Basis for the Interaction of Ethylene Glycol, Glycine, and Sarcosine Chains with Bovine Carbonic Anhydrase II: An Unexpected Manifestation of Enthalpy/Entropy Compensation.” J. Am. Chem. Soc., 128, Pp. 5802-5812. PDF

I. Gitlin, K. L. Gudiksen, and G. M. Whitesides. 2006. “Peracetylated Bovine Carbonic Anhydrase (BCA-Ac18) is Kinetically More Stable than Native BCA to Sodium Dodecyl Sulfate.” Journal of Physical Chemistry B., 110, Pp. 2372-2377. PDF

X. Jiang, J. N. Lee, and G. M. Whitesides. 2006. “Self-Assembled Monolayers in Mammalian Cell Cultures.” In Scaffolding in Tissue Engineering, edited by P. X Ma and J. Elisseff, ch. 14: Pp. 199-215. Ann Arbor, MI: CRS Taylor & Francis Group. 961.pdf