Carbonic Anhydrase and Protein-Ligand Binding

I. Gitlin, K. L. Gudiksen, and G. M. Whitesides. 2006. “Peracetylated Bovine Carbonic Anhydrase (BCA-Ac18) is Kinetically More Stable than Native BCA to Sodium Dodecyl Sulfate.” Journal of Physical Chemistry B., 110, Pp. 2372-2377. PDF
G. M. Whitesides and V.M. Krishnamurthy. 2005. “Designing Ligands to Bind Proteins.” Quarterly Reviews of Biophysics, 38, Pp. 385-395. PDF
K. L. Gudiksen, I. Gitlin, J. Yang, A. R. Urbach, D. T. Moustakas, and G. M. Whitesides. 2005. “Eliminating Positive Charged Lysine e-NH3+ Groups on the Surface of Carbonic Anhydrase has no Significant Influences on Its Folding from Sodium Dodecyl Sulfate.” J. Am. Chem. Soc., 127, Pp. 4707-4714. PDF
K. L. Gudiksen, A. R. Urbach, I. Gitlin, J. Yang, J.A. Vasquez, C.E. Costello, and G. M. Whitesides. 2004. “The Influence of the Zn(II) Cofactor on the Refolding of Bovine Carbonic Anhydrase after Denaturation with Sodium Dodecyl Sulfate.” Analytical Chemistry, 76, Pp. 7151-7161. PDF
E. Ostuni, B. A. Grzybowski, M. Mrksich, C. S. Roberts, and G. M. Whitesides. 2003. “Adsorption of Proteins to Hydrophobic Sites on Mixed Self-Assembled Monolayers.” Langmuir, 19, Pp. 1861-1872. PDF
J. R. Anderson, O. Cherniavskaya, G. S. Engel, I. Gitlin, L. Yuditsky, and G. M. Whitesides. 2002. “Analysis by Capillary Electrophoresis of the Kinetics of Charge Ladder Formation for Bovine Carbonic Anhydrase.” Analytical Chemistry, 74, Pp. 1870-1878. PDF
B. A. Grzybowski, A. V. Ishchenko, C. Y. Kim, G. Topalov, R. G. Chapman, D.W. Christianson, G. M. Whitesides, and E. I. Shakhnovich. 2002. “Combinatorial Computational Methods Give New Picomolar Ligands for a Known Enzyme.” Proc. Nat. Acad. Sci. USA, 99, Pp. 1270-1273. PDF
X. Qian, R. E. Holmlin, G. M. Whitesides, C. Y. Chen, M. Schiavoni, S. P. Smith, F. Assi, and M. G. Prentiss. 2002. “Measuring the Inhibition of Adhesion of Lectins to the Surface of Erythrocytes with Optically Controlled Collisions between Microspheres and Erythrocytes.” Journal of Physical Chemistry B, 106, Pp. 9159-9164. PDF
X. Chen, R. Ferrigno, and G. M. Whitesides. 2002. “Redox Properties of Cytochrome c Adsorbed on Self-Assembled Monolayers: A Probe for Protein Conformation and Orientation.” Langmuir, 18, Pp. 7009-7015. PDF
J. Rao, L. Yan, J. Lahiri, G. M. Whitesides, R. M. Weis, and H. S. Warren. 1999. “Binding of a Dimeric Derivative of Vancomycin with L-Lys-D-Ala-D-lactate in Solution and at a Surface.” Chemistry and Biology, 6, Pp. 353-359. PDF
J. Lahiri, L. Isaacs, B. A. Grzybowski, J. D. Carbeck, and G. M. Whitesides. 1999. “Biospecific Binding of Carbonic Anhydrase to Mixed SAMs Presenting Benzenesulfonamide Ligands: A Model System for Studying Lateral Steric Effects.” Langmuir, 15, Pp. 7186-7198. PDF
N. Horan, L. Yan, H. Isobe, G. M. Whitesides, and D. Kahne. 1999. “Non-Statistical Binding of a Protein to Clustered Carbohydrates.” Proc. Nat. Acad. Sci. USA, 96, Pp. 11782-11786. PDF
J. Gao, Q. Wu, J. D. Carbeck, Q. P. Lei, R. D. Smith, and G. M. Whitesides. 1999. “Probing the Energetics of Dissociation of Carbonic Anhydrase-Ligand Complexes in the Gas Phase.” Biophys. J., 76, Pp. 3253-3260. PDF
I. S. Choi, N. B. Bowden, and G. M. Whitesides. 1999. “Shape-Selective Recognition and Self-Assembly of mm-Scale Components.” J. Am. Chem Soc., 121, Pp. 1754-1755. PDF
J. Lahiri, L. Isaacs, J. Tien, and G. M. Whitesides. 1999. “A Strategy for the Generation of Surfaces Presenting Ligands for Studies of Binding Based on an Active Ester as a Common Reactive Intermediate: A Surface Plasmon Resonance Study.” Analytical Chemistry, 71, Pp. 777-790. PDF
J. Gao, M. Mrksich, M. Mammen, and G. M. Whitesides. 1998. “Affinity Capillary Electrophoresis: Using Capillary Electrophoresis to Study the Interactions of Proteins with Ligands.” In High Performance Capillary Electrophoresis: Theory, Techniques, and Applications, edited by M. G. Khaledi, 29th ed., 146: Pp. 947-972. New York: John Wiley & Sons, Inc. PDF
J. D. Carbeck, I. J. Colton, J. Gao, and G. M. Whitesides. 1998. “Protein Charge Ladders, Capillary Electrophoresis, and the Role of Electrostatics in Biomolecular Recognition.” Accounts of Chemical Research, 31, Pp. 343-350. PDF
D. N. Chin, A. Y. Lau, and G. M. Whitesides. 1998. “Studying How Different Terminal Groups Change the Motion of H2NSO2C6H4CONH(EG)3R When Bound to the Active Site of Human Carbonic Anhydrase II.” Journal of Organic Chemistry, 63, Pp. 938-945. PDF
I. J. Colton, J. R. Anderson, J. Gao, R. G. Chapman, L. Isaacs, and G. M. Whitesides. 1997. “Formation of Protein Charge Ladders by Acylation of Amino Groups on Proteins.” J. Am. Chem. Soc., 119, Pp. 12701-12709. PDF
G. B. Sigal and G. M. Whitesides. 1996. “Benzenesulfonamide-Peptide Conjugates as Probes for Secondary Binding Sites Near the Active Site of Carbonic Anhydrase.” Bioorg. & Med. Chem. Lett., 6, Pp. 559-564. PDF