Polymeric Polyvalency, Influenza, Others

2006
V.M. Krishnamurthy, L. A. Estroff, and G. M. Whitesides. 2006. “Multivalency in Ligand Design.” In Fragment-based Approaches in Drug Discovery, edited by R. Mannhold, H. Kubinyi, and G. Folkers, 34: Pp. 11-53. Weinheim: WILEY-VCH Verlag GmbH & Co. 963.pdf
963
2005
J. C. Love, L. A. Estroff, J.K. Kriebel, R.G. Nuzzo, and G. M. Whitesides. 2005. “Self-Assembled Monolayers of Thiolates on Metals as a Form of Nanotechnology.” Chemical Reviews, 105, Pp. 1103-1169. PDF
909
2001
M. Mourez, R. S. Kane, J. Mogridge, S. J. Metallo, P. Deschatelets, B. R. Sellman, G. M. Whitesides, and R. J. Collier. 2001. “Designing a polyvalent inhibitor of anthrax toxin.” Nature Biotechnology, 19, Pp. 958-961. PDF
750
2000
J. Rao, J. Lahiri, R. M. Weis, and G. M. Whitesides. 2000. “Design, Synthesis, and Characterization of a High-Affinity Trivalent System Derived from Vancomycin and L-Lys-D-Ala-D-Ala.” J. Am. Chem. Soc., 122, Pp. 2698-2710. PDF
692
1998
J. Rao, J. Lahiri, L. Isaacs, R. M. Weis, and G. M. Whitesides. 1998. “A Trivalent System from Vancomycin•D-Ala-D-Ala with Higher Affinity Than Avidin•Biotin.” Science, 280, Pp. 708-711. PDF
614
1996
S.-K. Choi, M. Mammen, and G. M. Whitesides. 1996. “Monomeric Inhibitors of Influenza Neuraminidase Enhance the Hemagglutination Inhibition Activities of Polyacrylamides Presenting Multiple C-Sialoside Groups.” Chemistry and Biology, 3, Pp. 97-104. PDF
494
M. Mammen, K. Helmerson, R. Kishore, S.-K. Choi, W. D. Phillips, and G. M. Whitesides. 1996. “Optically Controlled Collisions of Biological Objects to Evaluate Potent Polyvalent Inhibitors of Virus-Cell Adhesion.” Chemistry and Biology, 3, Pp. 757-763. PDF
497
G. B. Sigal, M. Mammen, G. Dahmann, and G. M. Whitesides. 1996. “Polyacrylamides Bearing Pendant a-Sialoside Groups Strongly Inhibit Agglutination of Erythrocytes by Influenza Virus: The Strong Inhibition Reflects Enhanced Binding through Cooperative Polyvalent Interactions.” J. Am. Chem. Soc., 118, Pp. 3789-3800. PDF
489
1993
M.A. Sparks, K. W. Williams, and G. M. Whitesides. 1993. “Neuraminidase Resistant Hemagglutination Inhibitors: Acrylamide Copolymers Containing a C-Glycoside of N-Acetylneuraminic Acid.” J. Med. Chem., 36, Pp. 778-783. PDF
371
W. Schmid, L. Z. Avila, K. W. Williams, and G. M. Whitesides. 1993. “Synthesis of Methyl a-Sialosides N-substituted with Large Alkanoyl Groups, and Investigation of Their Inhibition of Agglutination of Erythrocytes by Influenza A Virus.” Bioorg. & Med. Chem. Lett., 3, Pp. 747-752. PDF
370
1992
J. E. Kingery-Wood, K. W. Williams, G. B. Sigal, and G. M. Whitesides. 1992. “The Agglutination of Erythrocytes by Influenza Virus is Strongly Inhibited by Liposomes Incorporating an Analog of Sialyl Gangliosides.” J. Am. Chem. Soc., 114, Pp. 7303-7305. PDF
355
1991
A. Spaltenstein and G. M. Whitesides. 1991. “Polyacrylamides Bearing Pendant a-Sialoside Groups Strongly Inhibit Agglutination of Erythrocytes by Influenza Virus.” J. Am. Chem. Soc., 113, Pp. 686-687. PDF
299