Protein Charge Ladders

2008
G. F. Schneider, B. F. Shaw, A. Lee, E. Carillho, and G. M. Whitesides. 2008. “Pathway for Unfolding of Ubiquitin in SDS, Studied by Capillary Electrophoresis.” J. Amer. Chem. Soc., 130, Pp. 17384-17393.Abstract
PMCID: PMC2688835
PDF
1039
2006
K. L. Gudiksen, I. Gitlin, and G. M. Whitesides. 2006. “Differentiation of Proteins based on Characteristic Patterns of Association and Denaturation in Solutions of Sodium Dodecyl Sulfate.” Proc. Natl. Acad. Sci. USA, 103, Pp. 7968-7972. PDF
956
I. Gitlin, J. D. Carbeck, and G. M. Whitesides. 2006. “Why are Proteins Charged? Networks of Charge-Charge Interactions in Proteins Measured by Charge Ladders and Capillary Electrophoresis.” Angewandte Chemie International Edition, 45, Pp. 3022-3060. PDF
951
2004
K. L. Gudiksen, A. R. Urbach, I. Gitlin, J. Yang, J.A. Vasquez, C.E. Costello, and G. M. Whitesides. 2004. “The Influence of the Zn(II) Cofactor on the Refolding of Bovine Carbonic Anhydrase after Denaturation with Sodium Dodecyl Sulfate.” Analytical Chemistry, 76, Pp. 7151-7161. PDF
890
2003
I. Gitlin, M. Mayer, and G. M. Whitesides. 2003. “Significance of Charge Regulation in the Analysis of Protein Charge Ladders.” Journal of Physical Chemistry B, 107, Pp. 1466-1472. PDF
825
J. Yang, I. Gitlin, V.M. Krishnamurthy, J.A. Vasquez, C.E. Costello, and G. M. Whitesides. 2003. “Synthesis of Monodisperse Polymers from Proteins.” J. Am. Chem. Soc., 125, Pp. 12392-12393. PDF
860
2002
J. R. Anderson, O. Cherniavskaya, G. S. Engel, I. Gitlin, L. Yuditsky, and G. M. Whitesides. 2002. “Analysis by Capillary Electrophoresis of the Kinetics of Charge Ladder Formation for Bovine Carbonic Anhydrase.” Analytical Chemistry, 74, Pp. 1870-1878. PDF
772
2001
R. S. Kane, P. T. Glink, R. G. Chapman, J. C. McDonald, P. K. Jensen, H. Gao, L. Pasa-Tolic, R. D. Smith, and G. M. Whitesides. 2001. “Basicity of the Amino Groups of the Aminoglycoside Amikacin Using Capillary Electrophoresis and Coupled CE-MS-MS Techniques.” Analytical Chemistry, 73, Pp. 4028-4036. PDF
747
1999
J. D. Carbeck, I. J. Colton, J. R. Anderson, J. Deutch, and G. M. Whitesides. 1999. “Correlations Between the Charge of Proteins and the Number of Ionizable Groups They Incorporate: Studies Using Protein Charge Ladders, Capillary Electrophoresis, and Debye-Hückel Theory.” J. Am. Chem. Soc., 121, Pp. 10671-10679. PDF
676
J. A. Caravella, J. D. Carbeck, D. C. Duffy, G. M. Whitesides, and B. Tidor. 1999. “Long-Range Electrostatic Contributions to Protein-Ligand Binding Estimated Using Protein Charge Ladders, Affinity Capillary Electrophoresis, and Continuum Electrostatic Theory.” J. Am. Chem. Soc., 121, Pp. 4340-4347. PDF
658
1998
I. J. Colton, J. D. Carbeck, J. Rao, and G. M. Whitesides. 1998. “Affinity capillary electrophoresis: A physical-organic tool for studying interactions in biomolecular recognition.” Electrophoresis, 19, Pp. 367-382. PDF
600
J. Gao, M. Mrksich, M. Mammen, and G. M. Whitesides. 1998. “Affinity Capillary Electrophoresis: Using Capillary Electrophoresis to Study the Interactions of Proteins with Ligands.” In High Performance Capillary Electrophoresis: Theory, Techniques, and Applications, edited by M. G. Khaledi, 29th ed., 146: Pp. 947-972. New York: John Wiley & Sons, Inc. PDF
584
J. D. Carbeck, J. C. Severs, J. Gao, Q. Wu, R. D. Smith, and G. M. Whitesides. 1998. “Correlation Between the Charge of Proteins in Solution and in the Gas Phase Investigated by Protein Charge Ladders, Capillary Electrophoresis, and Electrospray Ionization Mass Spectrometry.” J. Phys. Chem. B, 102, Pp. 10596-10601. PDF
615
J. D. Carbeck, I. J. Colton, J. Gao, and G. M. Whitesides. 1998. “Protein Charge Ladders, Capillary Electrophoresis, and the Role of Electrostatics in Biomolecular Recognition.” Accounts of Chemical Research, 31, Pp. 343-350. PDF
603
1997
I. J. Colton, J. R. Anderson, J. Gao, R. G. Chapman, L. Isaacs, and G. M. Whitesides. 1997. “Formation of Protein Charge Ladders by Acylation of Amino Groups on Proteins.” J. Am. Chem. Soc., 119, Pp. 12701-12709. PDF
567
E. Cordova, J. Gao, and G. M. Whitesides. 1997. “Noncovalent Polycationic Coatings for Capillaries in Capillary Electrophoresis of Proteins.” Analytical Chemistry, 69, Pp. 1370-1379. PDF
526
J. Gao and G. M. Whitesides. 1997. “Using Protein Charge Ladders to Estimate the Effective Charges and Molecular Weights of Proteins in Solution.” Analytical Chemistry, 69, Pp. 575-580. PDF
542
1996
J. Gao, M. Mammen, and G. M. Whitesides. 1996. “Evaluating Electrostatic Contributions to Binding with the Use of Protein Charge Ladders.” Science, 272, Pp. 535-537. PDF
492
1995
M. Mammen, F. A. Gomez, and G. M. Whitesides. 1995. “Determination of the Binding of Ligands Containing the N-2,4-Dinitrophenyl Group to Bivalent Monoclonal Rat Anti-DNP Antibody Using Affinity Capillary Electrophoresis.” Anal. Chem., 67, Pp. 3526-3535. PDF
467
J. Gao, M. Mrksich, F. A. Gomez, and G. M. Whitesides. 1995. “Using Capillary Electrophoresis to Follow the Acetylation of the Amino Groups of Insulin and to Estimate Their Basicities.” Anal. Chem., 67, Pp. 3093-3100. PDF
468