%0 Journal Article %J Proc. Nat. Acad. Sci. USA %D 2002 %T Combinatorial Computational Methods Give New Picomolar Ligands for a Known Enzyme %A Grzybowski, B. A. %A Ishchenko, A. V. %A Kim, C. Y. %A Topalov, G. %A Chapman, R. G. %A Christianson, D.W. %A Whitesides, G. M. %A Shakhnovich, E. I. %K Nature Biotech %K Re-submitted to PNAS by fedex 12/13/01(title changed from %K Was sent to Science but rejected: will be resubmitted eventually. Also needs checklist (10/19/00) %B Proc. Nat. Acad. Sci. USA %V 99 %P 1270-1273 %8 2/5/02 %G eng %L 774 %F 783