Charge Regulation

2016
K. Kang, J-M. Choi, J. M. Fox, P. W. Snyder, D. T. Moustakas, and G. M. Whitesides. 2016. “Acetylation of Surface Lysine Groups of a Protein Alters the Organization and Composition of its Crystal Contacts.” J. Phys. Chem. B, 120, Pp. 6461-6468.Abstract
9.5.2, 9.5.4, 9.5.5
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1280
2012
K. A. Mirica, M. R. Lockett, P. W. Snyder, N. D. Shapiro, E. T. Mack, S. Nam, and G. M. Whitesides. 2012. “Selective Precipitation and Purification of Monovalent Proteins Using Oligovalent Ligands and Ammonium Sulfate.” Bioconjugate Chem., 23, Pp. 293-299.Abstract
PMCID: PMC3288307
PDF Supplemental
1142
2011
A. Lee, S. K. Y. Tang, C. R. Mace, and G. M. Whitesides. 2011. “Denturation of Proteins by SDS and by Tetraalkylammonium Dodecyl Sulfates.” Langmuir, 27, Pp. 11560-11574.Abstract
PMCID:3172379
PDF
1131
2010
B. F. Shaw, H. Arthanari, A. Lee, A. Durazo, D.P Frueh, M. P. Pollastri, B. Bilgicer, S. P. Gygi, G. Wagner, and G. M. Whitesides. 2010. “Neutralizing Positive Charges at the Surface of a Protein Lowers its Rate of Amide Hydrogen Exchange without Altering its Structure or Increasing its Thermostability.” J. Amer. Chem. Soc., 132, Pp. 17411-17425.Abstract
PMC3135700
PDF Supplemental
1102
2006
I. Gitlin, K. L. Gudiksen, and G. M. Whitesides. 2006. “Effects of Surface Charge on Denaturation of Bovine Carbonic Anhydrase.” ChemBioChem, 7, Pp. 1241-1250. 962.pdf
962
V.M. Krishnamurthy, L. A. Estroff, and G. M. Whitesides. 2006. “Multivalency in Ligand Design.” In Fragment-based Approaches in Drug Discovery, edited by R. Mannhold, H. Kubinyi, and G. Folkers, 34: Pp. 11-53. Weinheim: WILEY-VCH Verlag GmbH & Co. 963.pdf
963
2005
G. M. Whitesides and V.M. Krishnamurthy. 2005. “Designing Ligands to Bind Proteins.” Quarterly Reviews of Biophysics, 38, Pp. 385-395. PDF
941
K. L. Gudiksen, I. Gitlin, J. Yang, A. R. Urbach, D. T. Moustakas, and G. M. Whitesides. 2005. “Eliminating Positive Charged Lysine e-NH3+ Groups on the Surface of Carbonic Anhydrase has no Significant Influences on Its Folding from Sodium Dodecyl Sulfate.” J. Am. Chem. Soc., 127, Pp. 4707-4714. PDF
907
2002
J. R. Anderson, O. Cherniavskaya, G. S. Engel, I. Gitlin, L. Yuditsky, and G. M. Whitesides. 2002. “Analysis by Capillary Electrophoresis of the Kinetics of Charge Ladder Formation for Bovine Carbonic Anhydrase.” Analytical Chemistry, 74, Pp. 1870-1878. PDF
772
X. Chen, R. Ferrigno, and G. M. Whitesides. 2002. “Redox Properties of Cytochrome c Adsorbed on Self-Assembled Monolayers: A Probe for Protein Conformation and Orientation.” Langmuir, 18, Pp. 7009-7015. PDF
812
2001
R. E. Holmlin, X. Chen, R. G. Chapman, S. Takayama, and G. M. Whitesides. 2001. “Zwitterionic SAMs that Resist Nonspecific Adsorption of Protein from Aqueous Buffer.” Langmuir, 17, Pp. 2841-2850. PDF
738
1998
G. T. R. Palmore, H. Bertschy, S. H. Bergens, and G. M. Whitesides. 1998. “A methanol/dioxygen biofuel cell that uses NAD+-dependent dehydrogenases as catalysts: application of an electro-enzymatic method to regenerate nicotinamide adenine dinucleotide at low overpotentials.” Journal of Electroanalytical Chemistry , 443, Pp. 155-161. PDF
580
1994
J. Gao, F. A. Gomez, R. Harter, and G. M. Whitesides. 1994. “Determination of the Effective Charge of a Protein in Solution by Capillary Electrophoresis.” Proc. Nat. Acad. Sci. USA, 91, Pp. 12027-12030. PDF
424